Skin Rituals 'skin care cocktails' are a potent mixture of antioxidants, peptides and other innovative anti-aging ingredients. Together these products work synergistically to transform and regenerate your skin for a more youthful appearance. A fast absorbing, light & greaseless serum that leaves a velvety smooth finish on the skin.
Anti-Aging Complex with Resveratrol
Active Ingredients:
5% Metabiotics™ Resveratrol. Remarkable advances in anti-aging applications for skin resilience, including reductions in fine lines and improvement in skin tone, are being seen with Metabiotics™ Resveratrol.
Pichia pastoris, the microorganism used in the production of Metabiotics™ Resveratrol, was chosen chiefly due to its long history of use in the pharmaceutical industry where it is considered GRAS or generally recognized as safe by the FDA. Only recently has it been explored for its use in personal care applications. Pichia pastoris, like others of the Saccharomycetase genus to which it belongs, has the distinctive ability to express bio-actives that are capable of unique benefits, without application of human cell lines.
Collagen IV and anti-inflammatory synthesis activity is afforded through the complete metabolization of the resveratrol in the biofermentation process, targeting micro-inflammation and maintaining the structural integrity of skin cells through the dermal epidermal junction (DEJ). Metabiotics™ Resveratrol promotes firming and helps rebuild DEJ structural integrity.
In vitro studies were performed to determine the inhibitory benefits of Metabiotics™ Resveratrol on a full thickness tissue model to reduce expression of the anti-inflammatory enzyme cyclooxygenase 1 [COX1] along with its ability to promote the synthesis of Collagen IVA on the same tissue model. The results, in both cases, confirm with statistical significance that either a 1% or 2% treatment of Metabiotics™ Resveratrol reduces the levels of the COX1 enzyme and increases the amount of COLL IVA synthesis. In vivo, an anti-aging study has confirmed a reduction in fine lines and wrinkles following a 28-day application, as well as firming and lifting of the skin to reduce notable sagging that was present prior to treatment.
Key attributes include: Anti-Wrinkle Targets Expression Wrinkles Enhanced Skin Tone Skin Firming and Smoothing Collagen Synthesis Promoting Extra Cellular Matrix Non-Animal Derived Anti-Inflammatory
5% Argireline is a peptide (acetyl hexapeptide-3) that inhibits SNARE complex formation and catecholamine release, resulting in the reduction of the degree of existing facial wrinkles and demonstrated effectiveness against their development with regular use. Argireline reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes.
4% Matrixyl™ 3000 is an anti-aging product from Sederma. "Matrikine" is the term proposed for fragmented matrix peptides able to regulate cell activity. Matrixyl™ 3000 contains two matrikines, Pal-GHK and Pal-GQPR. Acting as messengers of cutaneous restructuration and repair, these two peptides work synergistically to restore and maintain the skin's youthful appearance.
3% Pepha™-Protect is a highly purified Watermelon extract with the ability to protect the DNA in skin cells from damage caused by UV-light induced free radicals. Pepha®-Protect is a skin protective active containing naturally occurring vitamins, carbohydrates and amino acids such as Citrulline. Under extreme conditions Watermelon plants develop their own defense system by producing Compatible Solutes. These are water soluble molecules, for example amino acids, which penetrate easily into the skin. Compatible Solutes also can naturally occur in the human body. Pepha®-Protect's synergistic composition is very strong in protecting the DNA of the skin’s fibroblasts and keratinocytes. Pepha®-Protect is a highly concentrated aqueous solution manufactured according to GMP standards.
The skin is increasingly exposed to free radicals. This can be partly explained by the decrease of the protective ozone layer and increased pollution due to our modern lifestyle. As a consequence, damage to the DNA, which can be irreversible, causes the appearance of mutations. The natural regeneration of the cells is reduced due to stress, aging and increasing amount levels of free radicals. Pepha®-Protect increases the natural defense system of the skin due to the synergistic acting effect of the vitamins, carbohydrates and Citrulline.
Compatible Solutes are able to protect important cell structures such as the DNA from destruction. Such compounds occur in organisms which survive under extreme conditions such as high salt concentration, heat or drought. Watermelon (Citrullus Lanatus) grows in the Kalahari Desert and exhibits high drought tolerances. Exposed to such stress the Melon produces its own defense system which Pentapharm then uses for Pepha®-Protect. In the Kalahari Desert, Watermelon is still used as a very important water source. The melon used for Pepha®-Protect is a cultivated plant growing under the same conditions as the wild one. Consequently Pentapharm Ltd's highly purified Watermelon extract nourishes the skin by its natural water binding habit. Pepha®-Protect is a preventative ingredient of choice to protect the skin against the breakdown of the DNA caused by UV-light and pollution.
1% Niacinamide is the active form of Vitamin B3. A safe, nonirritating cosmeceutical ingredient which research shows can offer a number of benefits in improving the appearance of aged and photodamaged skin. Studies have shown topical niacinamide to be effective in improving skin texture and the appearance of hyperpigmented spots, with improvement in overall blotchiness and the reduction of the severity of fine lines. It has been shown to stimulate collagen synthesis and production of ceramide, a lipid compound that contributes to the functional and structural integrity of the skin barrier. Theoretically, by improving barrier integrity, niacinamide may help the skin become more resistant to external irritants.
5% SymGlucan® is an exciting multifunctional, antiaging ingredient manufactured by Symrise. SymGlucan® is made by a patented technology which refines Beta-Glucan to produce a highly active soluble fraction. SymGlucan® has been clinically shown to penetrate the skin and help reduce the visible signs of aging. SymGlucan's unique delivery system stimulates fibroblast growth and collagen synthesis which reduces the appearance of wrinkles. Studies have also demonstrated SymGlucan® to be an excellent moisturizer that provides even better long-term moisturization than Hyaluronic Acid. SymGlucan helps to restore skin's youthful elasticity and softness.
